【Animal Modeling】-Morphological characteristics of kidneys in Meriones gerbils and SD rats

  Purpose: To lay a foundation for studying the meridian gerbil populations and provide data support for researchers who use meridian gerbils as the research object to develop animal models.

  Method: In this study, we investigated wild snails and experimental SD rats, observed the morphological characteristics of the two kidneys, and observed morphological indicators such as kidney tissue, kidney-to-body ratio, nephron density, etc. And measured other parameters. For comparison.

  Results: Comparison of two rats: renal medulla to cortical area ratio, renal medulla to cortical area ratio, renal medullary area to renal cross-sectional area ratio, unit area proximal and distal curvature ratios are statistically different. significance. The ratio of the two kidneys to the body and the density of nephrons also vary greatly between species.

  Conclusion: The morphological and histological characteristics of the kidney indicate that the morphological structure of the wild mammalian kidney has a higher correlation with the urine concentration ability, and it is drought-tolerant and conforms to the characteristics of the mammalian kidney.