动物造模,lr4基因敲除 z-bio 2021-10-09 928

　　Objective: How to study the similarities and differences in growth and reproduction between Tlr4 knockout mice and KM mice?

　　Method: Select 20 Tlr4 knockout mice and KM mice, each half male and half male, and measuring for 4-12 weeks. Mouse weight and body length, 2 growth rates, 20 randomly selected, do you count as a cage (1 female and 1 male) and the second offspring?

　　Results: At P0.05, the body weight and growth rate of Tlr4 knockout mice were significantly lower than that of KM mice. At other times, the body length and growth rate of Tlr4 knockout mice were significantly smaller than that of KM mice, and Pu003c0.05 and Tlr4 knockout mice were significantly smaller than KM mice. Mouse, Pu003c0.05?

　　Conclusion: Does Tlr4 gene knockout have a sustained effect on the growth, development and reproduction of mice?