动物造模,口腔颊黏膜癌 z-bio 2021-07-02 265

　　OBJECTIVE: To construct a differentially expressed miRNA and mRNA expression profile of Chinese hamster oral and buccal mucosal cancer to predict the onset and incidence of OSCC in advance.

　　Method: Through a new generation of GeneOntology enhancement and KEGG pathway analysis to establish a high-throughput sequencing technology for miRNA and mRNA expression profiles, predict the miRNA and mRNA related to the development of OSCC?

　　Result: Successfully constructed expression profiles of miRNAs and mRNAs with different expression levels. Have you found a total of 11 known miRNAs in Chinese hamster oral and buccal mucosal cancer? Three new miRNAs are significantly differentially expressed, and 194 mRNAs are differentially expressed. Can one miRNAs regulate multiple mRNAs? Can multiple miRNAs target and regulate specific mRNAs?

　　Conclusion: This experiment forms a complex regulatory network by regulating the differentially expressed miRNA mRNA in OSCC. The development and pathogenesis of oral cancer, the development and pathogenesis of oral cancer, and the clinical treatment and prognosis?