【Animal Modeling】-How to compare the bone mineral density in different bone regions of female Wistar rats of different ages

  Purpose: Do you provide reference values for bone mineral density in different bone regions of female Wistar rats of different ages?

  Method: 6 months old? 10 months? 12 months? Thirty female Wistar rats with 24 SPF were selected. At the age of 30 months, the bone density of the rat's head, upper limbs, thighs, trunk, ribs, pelvis, spine and whole body was measured sequentially with a dual-energy X-ray bone densitometer. Do you want to compare the changes in bone mineral density between different bone regions?

  Result: With age, the bone density of the head, upper limbs, thighs, trunk, ribs, pelvis, spine and whole body of female rats increased rapidly. The bone mineral density values of the head, upper limbs, thighs, trunk and ribs of the rats were significantly or significantly higher than the whole body bone mineral density values. In the same month (P0.05), all three correlation analyses were significantly positive (Pu003c0.01). )?

  Conclusion: This article provides some background data on bone biological indicators of female Wistar rats. Want to supplement the basic reference materials for Wistar rat bone metabolism research and its application in the field of biomedicine?