Kinesin-2 z-bio 2021-07-02 371

　　The kinesin-2 protein is a subfamily of the kinesin superprotein family, and its members include KIF3A, KIF3B, KIF3C and KIF17. The members of the kinesin-2 family, as molecular motor proteins, participate in the transport of various intracellular protein complexes and vesicles. These are very important for cells to perform various biological functions. In recent years, it has been discovered that kinesin-2 plays an important role in the material transport of cilia. Its functional defects lead to abnormal cilia development, which affects the development of tissues and organs, and ultimately a variety of cilia disorders. This review introduces the latest developments in kinesin-2 research. And it focuses on the new progress of the kinesin-2 family members in the study of model organisms.