动物造模,口腔溃疡动物模型 z-bio 2021-10-13 939

　　Purpose: How to establish a SD rat oral ulcer animal model through a variety of chemical combustion methods and screen the best plan to evaluate the treatment effect?

　　Method: Should 50 SD rats be randomly divided into 5 groups? A crystalline ulcer model of glacial acetic acid or NaOH was established on the lip and cheek mucosa of incisors. The second burn group: After the ulcer was formed, the ulcer model was reconstructed in situ with 50° glacial acetic acid. Has the lip mucosa of the alveolar bone healed? Have you observed the condition of the mucous membrane? The incidence of ulcers, healing time and histopathological changes?

　　Result: The concentration of glacial acetic acid ulcer in the alveolar lip mucosa is 50°, and the incidence of ulcer is very high. The morphological rules are easy to observe. The average healing time and histological characteristics are similar to those of humans, and the overall contrast is very good. In other groups? Is it not easy for people with secondary burning to form ulcers?

　　Conclusion: 50? Can acetic acid treatment of alveolar mucosa provide a better oral ulcer model, which can be used as an ideal model for studying ulcer treatment? Isn’t it suitable to reconstruct the ulcer model at the same site?