【Animal Modeling】-Why establish a rat model of uterine fibroids tissue transplantation?

  Objective: To establish a rat model of uterine fibroids with tissue inhibitor transplantation immunosuppression, and to provide a new animal model for the study of uterine fibroids.

  Method: From 2 weeks before the operation to the end of the experiment, did you give the rats a compulsory feeding immunosuppressant? Mycophenolate mofetil (MMF)? Twenty Wistar rats were randomly divided into four groups based on various hormones supplemented after peritoneal transplantation. Samples were taken 4 weeks after the operation to observe the morphology and tissue morphology of group A (fenmax), group B (estradiol), group C (Duffton), group D (control group), uterine fibroids?

  Result: The modelling success rate of group A is 90? The modelling success rate of group B is 40? The modelling success rate of group C is 0? Conclusion: The success rate of rat uterine fibroids transplantation tumor model is high and the cost is low.