动物造模 z-bio 2021-07-08 285

　　Objective: To explore the effect of natural hot spring water on lipid peroxidation in aged mice.

　　Method: 8-month-old SPF male ICR mice were adaptively reproduced for 5 days, fasted for 16 hours, blood was collected, and serum malondialdehyde (MDA) content was determined. According to the content of MDA, ICR mice were randomly divided into two groups: a natural hot spring water group and a tap water control group. The natural mountain spring water group drinks free natural mountain spring water, and the tap water management group drinks free tap water for two consecutive months, and fasts for 16 hours after drinking for one and two months. Oxide dismutase (SOD) activity.

　　Result: Two months after giving natural hot spring water, compared with the tap water control group, the content of malondialdehyde (MDA) in the natural hot spring water group was significantly reduced (Pu003c0.05), and the active superoxide dismutase (SOD) was reduced. ) This is not a significant gender difference.

　　Conclusion: Drinking natural hot spring water has a certain effect on reducing lipid peroxidation in aged mice.