动物造模 z-bio 2021-07-16 561

　　Objective: To study the protective effect of sunscreen coenzyme Q10 on mice.

　　Method: 36 mice were randomly divided into groups. After peeling off the skin, apply each corresponding cream. The normal control group did not receive any treatment, and the other groups received ultraviolet radiation. The mice bleed continuously for 8 weeks and were sacrificed for indicator detection.

　　Results: Compared with normal mice, the model group had rough skin, wrinkles, stratum corneum, T-SOD and GSH-Px activities were significantly reduced, and white blood cell and MDA counts increased and decreased. done. The content increased significantly (Pu003c0.05). Compared with the model group, the mice in the ginsengase Q10 sunscreen group had smoother skin, no stratum corneum, increased T-SOD activity, and significantly decreased white blood cell and hemoglobin content. The blood cell count and MDA content of the positive control group were low (Pu003c0.05), the skin of the mice was smooth, the stratum corneum did not fall off, the activity of GSH-Px increased, and the white blood cells increased. The count and MDA content have been reduced. (Pu003c0.05).

　　Conclusion: Ginseng coenzyme Q10 sunscreen has an anti-ultraviolet effect, and its preventive effect is equivalent to that of methoxycinnamic acid coenzyme Q10 cream.