动物造模 z-bio 2021-10-07 615

　　Treat diseases through external electrical stimulation, collect neuroelectric signals, detect neurofeedback neuroelectric signal stimulation to external stimuli, receive, collect, and transmit, develop corresponding signal analysis equipment, clinical medicine, biomedicine, electronics and other hot cross-topics. The results of nerve electrical stimulation and nerve electrical signal analysis are widely used in clinical medicine such as disease analysis, treatment and monitoring, and the performance requirements of related stimulation and signal detection modules are getting higher and higher.

　　Deep brain stimulation (DBS) is an effective method for the treatment of a variety of neuropsychiatric diseases, including Parkinson's disease (PD), essential tremor and primary dystonia. In 1987, A. Benabid discovered that radiofrequency electrical stimulation was used to destroy the ventral intermediate nucleus (VIM) of the thalamus, but it could improve conditions similar to tremor. This innovative therapy quickly became popular because electrical stimulation is reversible, programmable, and can be performed on both sides of the brain. This is the origin of brain electrical stimulation therapy, that is, deep brain electrical stimulation.

　　DBS treatment mainly uses positioning technology and microelectrode recording technology, inserting electrodes into specific cell nuclei of the brain, and using continuous high-frequency pulse electrical stimulation to inhibit abnormal brain nucleus discharge and achieve the therapeutic effect at the same time. , It can record electrical nerve signals through microelectrodes.