【Animal Modeling】-Research Progress of Hollow Fiber Tumor Model

  The hollow fiber tumor model or HollowFiberAssay (HFA) is a new type of anti-cancer drug pre-screening model designed by the National Cancer Institute (NCI), which is simple, fast, accurate, simple and feasible. Initial screening. Evaluation of in vivo effectiveness. In recent years, it has been widely used in the research and development of anti-tumor drugs, and new improvements, optimizations and applications have been continuously carried out.

  This article systematically reviews the advantages and characteristics of the hollow line tumor model in anti-tumor screening, as well as the latest application progress in the past ten years. The study believes that HFA is playing an increasingly important role in the research of anti-tumor drugs. Improved models of tumor drugs and HFA This has a wide range of potential applications in individualized cancer treatment and mechanism research.