In recent years, degenerative intervertebral disc disease (IDD) has received widespread attention due to the increase in its incidence and age of onset. The resulting spinal diseases have reduced the quality of human life to varying degrees. The uncertainty of its degenerative mechanism complicates further research on the etiology and pathology of intervertebral disc degeneration.
This article summarizes the current main modeling methods based on domestic and foreign degenerative disc diseases related literature. It is best to choose a model that can be fully simulated by comparing the differences between different animal models of degenerative disc disease. Human degenerative disc disease.