【Animal Modeling】-Comparative study of ADHD experimental animal models

  Objective: To summarize the research status of ADHD animal models, analyze the advantages and disadvantages of various models, provide references for establishing ideal ADHD animal models, and provide new ideas for future ADHD experimental research.

  Method: Collect relevant literature on ADHD animal models, analyze and summarize the source and scope of application of various models, and summarize their advantages and disadvantages.

  Results: ADHD models are mainly divided into four types: genetic models, nerve injury models, artificial screening models and environmental adaptation models. These four models have different modeling goals and different application ranges, and each has advantages and disadvantages.

  Conclusion: According to relevant indicators, there is no ideal animal model for ADHD. SHR rat is currently a relatively complete model. The selection of animal models needs to be screened according to the purpose of the research. The establishment of an ideal ADHD animal model is an important research direction.