Researchers use mouse models to verify that Alzheimer's disease comorbids cerebrovascular disease can aggravate disease symptoms

  According to a new study, two diseases, Alzheimer's disease and cerebrovascular accident, can exacerbate the symptoms of this disease. Recently, the two research groups have conducted research on the subject at the same time, and verified this conclusion from various aspects through mouse models.

  A study by murphy and his team integrated the effects of type 2 diabetes, Alzheimer's disease, and cerebrovascular accident on mouse models. Wilcock and her team also studied the effects of Alzheimer's disease and hyperhomocysteinemia in mouse models. High levels of homocysteine are associated with many diseases, including cerebrovascular accidents.

  The research of the two teams came to similar conclusions. Although the key pathological features of Alzheimer's disease have not changed, the learning ability and memory of the patient are even significantly reduced. In mouse model studies, the simultaneous development of Alzheimer's disease and cerebrovascular disease increased the severity of the disease. The results of these studies can explain why 40 patients with Alzheimer's disease still suffer from cerebrovascular disease and may help treat future diseases.