The research team of Dr. Taki Tiraihi of the Tarbia Tomodares Medical College in Iran found that motor neuron-like cell transplantation combined with glial cell-derived neurotrophic factor can reduce the formation of syringomyelia in injured rats and increase the density of nerve cells. Cell transplantation site; the promotion effect on the recovery of motor function of injured rats is more obvious, and the effect is far better than other methods.
Dr. Taki Tiraihi from the research group of Taki Tiraihi School of Medicine, Tabyato Modares University, Iran, conducted animal experiments on this project. Seven days after the spinal cord contusion of the rat, the motor neuron-like cells induced by adipose stem cells were injected into the center and tail area of the rat spinal cord, and the glial cell-derived neurotrophic factor-gelatin sponge complex was transplanted into the rat spinal cord.
"The results show that motor neuron-like cell transplantation combined with glial-derived neurotrophic factor can reduce the formation of syringomyelia in injured rats, increase the density of neurons at the cell transplantation site, and promote the recovery of motor function. It is obvious in rats with spinal cord injury, and its effect is better than that of glial-derived neurotrophic factor, adipose stem cells and motor neuron-like cells alone. This indicates that this combination therapy is a potential method of repairing spinal cord injury.