动物造模,抽动障碍动物模型 z-bio 2021-08-16 653

　　Tic disorder is a common neurodevelopmental disorder in childhood, mainly manifested as involuntary repetitive sudden movements and vocalization. May be accompanied by attention deficit hyperactivity disorder, learning disabilities, obsessive-compulsive disorder and behavioral disorders. It will have a serious impact on children's learning, social adaptability and mental health development. However, its etiology, pathogenesis and pharmacological mechanism are not yet fully understood. These basic studies need to be further studied and verified through animal models.

　　At present, there are many ways to establish tic disorder models, mainly based on the possible causes of the disease, such as neurotransmitter abnormalities, immune dysfunction, genetic factors, etc., but they are all fully capable animals, and no model can satisfy tic disorders. Performance.