【Animal Modeling】-American research says soybean oil affects the nervous system of mice

  A research team from the University of California, Riverside published a research report in the latest issue of the Journal of Endocrinology, stating that soybean oil, one of our main daily edible oils, not only causes obesity and diabetes, but is also related to changes in the nervous system. , Can affect neurological diseases such as autism, Alzheimer's disease, anxiety and depression.

  According to data from the US Department of Agriculture, soybean oil is by far the most produced and consumed edible oil in the United States, but studies have shown that it is likely to be unhealthy for humans. As early as 2015, the same research team at the University of California, Riverside found that soybean oil can induce obesity, diabetes, insulin resistance and fatty liver in mice; Lower acid content will reduce the risk of obesity and insulin resistance. In the latest study, the research team found that soybean oil has a significant effect on mouse hypothalamus, whether it is traditional soybean oil or genetically modified soybean oil with reduced linoleic acid content.

  In the latest study, researchers compared the effects of traditional soybean oil, genetically modified soybean oil with reduced linoleic acid content, coconut oil, and coconut oil supplemented with stigmasterol on male mice. They found that soybean oil can cause abnormal gene expression and oxytocin system in the mouse hypothalamus. The dysregulated genes are related to inflammation, neuroendocrine, neurochemistry, and insulin signaling. Researchers believe that this will not only affect the energy metabolism of mice, but also affect the normal brain function of mice and diseases such as autism and Parkinson's disease.

  It is important to point out that there is no evidence that soybean oil can cause these diseases, and these findings only apply to soybean oil, not to other soybean products such as tofu, soy milk, soy sauce, and other vegetable oils.

  The research team is still not sure which chemicals in soybean oil caused the changes in the hypothalamus of mice, but they have ruled out linoleic acid and stigmasterol. The researchers said that finding the "culprit" is their key research goal in the future, and their current advice to people is to reduce the consumption of soybean oil.