动物造模,动物实验 z-bio 2021-09-14 210

　　A team led by researchers from Imperial College London found through animal experiments that the combined use of two different anti-malaria vaccines has better anti-malarial effects than either vaccine alone.

　　Malaria is a disease caused by the plasmodium. It is spread by mosquito bites. Its symptoms include fever, headache, and vomiting. If not treated in time, it can be life-threatening.

　　The research team tested two types of malaria vaccines in the experiment, TBV and PEV, both of which are still in the process of clinical trials at different stages. In this experiment, the team used mice and a genetically modified parasite that shares certain characteristics with the malaria parasite.

　　The research team reported in the American journal "Electronic Life" that animal experiments show that these two vaccines, if used alone, can reduce the risk of malaria by 48% and 68%, respectively. If the two are used in combination, the risk of infection can be reduced. 91%.

　　One of the authors of the report, Imperial College scholar Andrew Braggborough said that achieving this effect will have a positive impact on public health, especially in areas where malaria is more common. Next, the researchers plan to verify the effect of combining different vaccines in a more complex environment.