动物造模 z-bio 2021-10-18 638

　　Purpose: To compare the four test results (PT, APTT, TT, FIB) of experimental animal SD rats and human blood coagulation reagents of imported and domestic brands of different manufacturers to see if there is a difference between them.

　　Method: select SPF grade SD rat and human blood coagulation specimens, and use domestic and imported blood coagulation reagents of two different brands to detect the four indicators of PT, APTT, TT and FIB blood coagulation.

　　Results: Two different brands of blood coagulation reagents had differences in the detection results of four indicators of rat blood coagulation. The detection results of rat blood coagulation indicators PT, APTT, and FIB domestic reagents were higher than those of imported reagents (P<0.05); rat blood The coagulation index TT test result of imported reagents was higher than that of domestic reagents (P<0.05); while there was no significant difference in human blood coagulation specimens.

　　Conclusion: There may be differences in the results of the four blood coagulation tests (PT, APTT, TT, FIB) of SD rats with blood coagulation reagents of different manufacturers, and each laboratory should establish corresponding background data according to their needs.