动物造模 z-bio 2021-10-18 409

　　The team of Dr. Feng Zhouyan from Zhejiang University in China used a microelectrode array to monitor the activity of neurons in the hippocampus of rats and found that the felt stimulus of the tail clip can induce different types of neurons to produce different responses. This study provided new clues to the information handling mechanism in the hippocampus.

　　The hippocampus of the brain is responsible for completing learning and memory, but its processing mechanism regarding the input information that the outside world feels is unclear.

　　The team of Dr. Feng Zhouyan of Zhejiang University in China used a microelectrode array to monitor the activity of neurons in the hippocampus of rats, and found that the felt stimulation of the tail can induce different types of neurons to produce different responses. Among them, the firing of pyramidal neurons decreases, while the firing of inhibitory interneurons increases. Moreover, the test results of applying electrical stimulation directly to the input channel of pyramidal neurons also indicated that the excitability of pyramidal neurons decreased during the somatosensory stimulation of the tail clamp.

　　These research results provide new clues to the information handling mechanism in the hippocampus. In addition, since the hippocampus is a prone area for brain diseases such as epilepsy, the inhibitory effect of somatosensory stimulation can also provide new ideas for treating diseases related to the hyperexcited state of nervous tissue. Relevant literature was published in the "Chinese Neural Regeneration Seminar (English Edition)" magazine, June 2014, issue 11.

　　The hippocampus of the brain is responsible for completing learning and memory, but its processing mechanism regarding the input information that the outside world feels is unclear.

　　The team of Dr. Feng Zhouyan of Zhejiang University in China used a microelectrode array to monitor the activity of neurons in the hippocampus of rats, and found that the felt stimulation of the tail can induce different types of neurons to produce different responses. Among them, the firing of pyramidal neurons decreases, while the firing of inhibitory interneurons increases. Moreover, the test results of applying electrical stimulation directly to the input channel of pyramidal neurons also indicated that the excitability of pyramidal neurons decreased during the somatosensory stimulation of the tail clamp.

　　These research results provide new clues to the information handling mechanism in the hippocampus. In addition, since the hippocampus is a prone area for brain diseases such as epilepsy, the inhibitory effect of somatosensory stimulation can also provide new ideas for the treatment of diseases related to the hyperexcited state of nervous tissue