[Animal Modeling]-Parasitic Infection and Drug Purification Effect of Meriones in a Closed Group

  Purpose: To lay the foundation for the establishment of a clean-level gerbil population, and to provide a reference for the establishment of parasite detection standards for gerbils.

  Methods: Investigate and study the parasite infection of Meriones gerbils in a closed group. Three drugs, tetramethrin, permethrin, praziquantel, and tinidazole, were selected and divided into high, medium and low doses for the gerbils. Observation Repelling of parasites in and out of the meridian gerbils.

  Result: Two kinds of endoparasites, Tritrichomonas murine and Hymenoderma brevisiae, were detected in the meridian gerbils, and the ectoparasites included rat meat mites. The high, medium, and low dose groups can kill the carnivorous mites on the meridian gerbils to varying degrees. The meridian mites can get rid of the meat on the meridian gerbils by bathing the meridian gerbils with 1% tetramethrin·permethrin three times. Mites, the number of animals with mites is zero. The praziquantel middle-dose group (31 mg/kg) has the effect of completely killing Hymenopsis brevis in the meridian gerbils, and it is the best dose. The middle dose group of tinidazole (42 mg/kg) is the best dose to purify tritrichomoniasis in the meridian gerbils.

  Conclusion: The existing meridian gerbils are infected with Tritrichomoniasis and Hymenothrix brevis, and there are parasitic mites outside the body. Three antiparasitic drugs have the effect of selectively repelling these parasites.