【Animal Modeling】-Aseptic pig growth, blood and organ related index determination

  Objective: To establish background data of multiple physiological data of sterile Taihu pigs.

  Method: Four 25-day sterile pigs and four common-litter populations with a male-female ratio of 3:1 were used to measure and compare blood routine, biochemical, immunoglobulin, and main organ development indicators. The allometric growth model is used to analyze the allometric growth of the main organs relative to body weight.

  Results: (1) There were significant differences in 12 blood routines and 8 blood biochemical indexes between sterile pigs and ordinary pigs (P<0.05); (2) The average body weight and serum IgM of sterile pigs and ordinary pigs The expression level difference reached a significant level (P<0.05), and sterile pigs lacked mesenteric lymph nodes; (3) The heart, spleen and stomach of sterile pigs showed negative allometric growth with body weight (allometric growth index b<1), The allometric growth index of the intestine and body weight is 1.78, which is a positive allometric growth; while the heart, stomach and intestines of ordinary pigs have negative allometric growth with body weight (b<1), and the allometric growth index of kidney and body weight The largest is 1.20, showing positive allometric growth.

  Conclusion: The difference in microbiological grades affects the development of pig body weight, blood, organs, and immune system.