动物造模 z-bio 2022-01-06 591

　　Objective To explore the inhibitory effect of a common commercial camellia powder on the increase in blood lipids caused by high-fat diet (HFD).

　　Methods Forty male SD rats were selected and randomly divided into 5 groups according to their body weight. The normal control group was given control feed, and the rest of the groups were given high-fat feed, respectively. After a week, the gavage was stopped for 2 weeks. From the second week onwards, blood was collected from the submandibular vein every weekend to test the serum lipid level.

　　Results At the weekend of 2-6, the total cholesterol level of the simple high-fat diet group was significantly higher than that of the normal control (P<0.001, P<0.05, P<0.01, P<0.01, P<0. 05). From 2 to 4 weekends, the total cholesterol of the low-dose camellia group was significantly lower than that of the simple high-fat diet group (P<0.05, P<0.05, P<0.01). On the weekend of 3 to 4, the triglycerides of the high-dose Camellia oleifera group were significantly lower than those of the simple high-fat diet group (P<0.05, P<0.01).

　　Conclusion The Camellia oleifera powder can inhibit the increase in blood lipids caused by a high-fat diet.