动物造模 z-bio 2022-06-29 365

　　Objective: To investigate the anti-fatigue effect of maca extract on sports.

　　Methods: 50 male Wistar rats were randomly divided into: ① control group: normal feeding, no swimming, gavage with the same volume of distilled water; ② simple swimming group: swimming, gavage with the same volume of distilled water; ③ swimming + drug administration group: swimming, And respectively gavage maca extract 4.0, 8.0 and 16.0 g/(kg·bw). 10 animals per group. Using circulating water to swim freely, rats were given 4.0, 8.0 and 16.0 g/(kg·bw) maca extract for 15 consecutive days. On the 16th day, samples were taken to measure hepatic lipid peroxidation (LPO) and superoxide disproportionation. enzyme (SOD), glutathione peroxidase (GSH-Px) and liver glycogen levels.

　　Results: Compared with the pure swimming group, after 15 days of administration of maca extract 4.0, 8.0 and 16.0 g/(kg·bw), the sinking times of the rats decreased by 27.44%, 42.86% and 64.11%, respectively (P<0.01). ), the swimming time before sinking and the total swimming time were prolonged by 18.99%, 64.46%, 90.69% and 37.12%, 56.23% and 94.72% respectively (P<0.01), and the LPO level was decreased by 31.31%, 42.00% and 56.95% respectively. (P<0.01), SOD, GSH-Px and liver glycogen levels increased by 25.92%, 31.82%, 62.09%, 12.33%, 23.01%, 46.36% and 17.83%, 44.69%, 62.99%, respectively (P<0.01 ).

　　Conclusion: Maca extract can reduce the level of liver LPO, increase the level of liver glycogen, improve the activities of SOD and GSH-Px, enhance exercise endurance and anti-fatigue.