动物造模 z-bio 2022-02-25 469

　　Objective: To investigate the effects of maca extract on the toxicity and immune organs of mice.

　　METHODS: BALB/c mice were given maca extract for 15 days to observe the toxic effects of maca on mice, and weigh the thymus and spleen.

　　RESULTS: The cumulative oral dose of mice within 24 hours was 320 g/(kg·bw), and there was no toxic reaction in the animals. After 16.0, 32.0, and 64.0 g/(kg·bw) of maca extract for 15 days, the weight of thymus increased by 36.84%, 89.47%, and 107.89%, and the weight of spleen increased by 44.83%, 62.01%, and 89.66%, respectively, compared with the control group. Compared with the control group, the difference was significant (P<0.05~ 0.01).

　　Conclusion: Maca extract can increase the weight of immune organs and improve immune function with low toxicity.