【Animal Modeling】-Scientists find that HIV in monkeys can fight drugs within a few days

  According to Singapore's "Lianhe Zaobao" recently reported that the latest research has found that the monkey version of HIV is able to evade the attack of anti-AIDS drugs a few days after entering the body.

  If the same is true of people infected with HIV, the new research report found that those infected would have to receive treatment at an "extremely early" stage.

  Not long ago, the medical community announced that the American girl "Mississippi Baby" who started receiving retroviral drugs 30 hours after birth, had been "cured" after 18 months of continuous treatment, but in July this year, it was found that HIV in her body had returned from ashes. .

  A key challenge in curing AIDS is that HIV has a hiding place, the report said, in infected immune cells. HIV DNA can lie dormant within infected immune cells for years, avoiding interference from antiretroviral drugs or the immune system.

  For the vast majority of patients, as long as the drug is stopped, the virus will soon begin to replicate, which means that the patient must take the drug for life.

  It's unclear when and how HIV finds these hiding cells when it invades the body.

  New research has found that rhesus monkeys infected with simian HIV have virus-hiding cells in their bodies "surprisingly early" after infection.

  The monkeys were treated 3, 7, 10 and 14 days after infection, but as soon as the drug was stopped, the virus started to replicate, although the virus replicated more slowly in the monkeys who received the treatment earlier.