动物造模,磁共振 z-bio 2022-03-12 651

　　OBJECTIVE: Based on 3.0 T magnetic resonance imaging (MRI) technology, the morphological and anatomical structure of the WHBE rabbit brain was observed in vivo, and the basic biological data of the WHBE rabbit brain imaging were accumulated, so as to provide background information for further expanding the application of WHBE rabbits.

　　METHODS: Nine adult male WHBE rabbits were anesthetized with 3% sodium pentobarbital solution intravenously, and underwent 3.0 T MRI and routine cross-sectional and sagittal scans with a special coil for the brain of the rabbit, and the various structures of the brain were measured and analyzed. .

　　Results: The sagittal and cross-sectional T2WI or T1WI images of the living WHBE rabbit brain were successfully obtained by MRI scanning, and the basic structures such as the olfactory bulb, cerebrum, cerebellum and pituitary of the living WHBE rabbits could be completely and clearly observed, and 4 rabbit brains were found. In T2WI, the left and right temporal lobe hippocampus showed high signal, and the corresponding areas showed low signal on T1WI, and the rest were normal. At the same time, the reference values of the frontal lobe, hippocampus, brain, lateral ventricle, pituitary and other related anatomical structures were obtained.

　　Conclusion: Using a 3.0 T magnetic resonance imaging system and a special coil for rabbit brain, various morphological and anatomical structures of the WHBE rabbit brain can be clearly observed, and the basic data of WBHE rabbit brain imaging have been preliminarily established.