动物造模 z-bio 2022-03-30 412

　　Objective: By comparing with the original goat anesthesia method, to observe the anesthesia effect of the improved anesthesia method, and to provide theoretical and practical reference for goat anesthesia during animal modeling.

　　Methods: A total of 72 goats were selected to make tibial fracture models, 36 were given the original anesthesia method, i.e., intramuscular injection of Sumianxin combined with diazepam (group A), and 36 were given the improved anesthesia method, i.e., intramuscular injection of Sumianxin, Diazepam combined with pump propofol (group B). The times of struggle, the total dose of chasing hypnosis, the lethality rate of anesthesia and the recovery time of the goat were observed.

　　RESULTS: The lethality rate of animals in group A was 16.67%, and no animals died in group B; the number of animals struggling, the total dose of new accelerative sleep, and the recovery time of group A were higher than those of group B, and the difference was statistically significant (P<0.05).

　　Conclusion: The improved anesthesia method can reduce the number of animals struggling, reduce the dosage of anesthetics, and reduce the mortality of animals.