大脑麻醉 z-bo 2020-08-17 485

　　One of the biggest secrets of anesthesia is that the patient temporarily becomes completely unresponsive during the operation and then wakes up again without losing memory and skills. A researcher said: "Recovering from anesthesia is not only the result of the "failure" of anesthesia, but also a brain looking for the active state of its circuit through the active state, which makes possible active states possible.

　　The new findings indicate that the brain after anesthesia needs to cross a specific "center" to regain consciousness. .. We recorded the general activity status of specific brain groups in anesthetized mice. In the image above, the longest is shown in red, and the shortest is shown in yellow and green.

　　A new study by Dr. Andrew Hudson, associate professor of anesthesiology at the David Geffen School of Medicine at the University of California, Los Angeles, and his colleagues provides important clues about the normal structural control of the brain by conscious processes from unawareness. Provide research results are currently published online on PNAS. Hudson said that previous studies have shown that at the surgical level of anesthesia, the anesthetized brain is not "stationary", but has undergone a certain mode of activity and changes naturally over time. statement. In the current study, the team recorded bioelectrical activity in several brain regions related to alertness and consciousness in a rodent model of isoflurane inhalation anesthesia. Then, just like treating patients in an operating room, slowly reduce the amount of anesthesia, detect how the brain's bioelectric activity changes, and look for common activity patterns in all subjects. it is. Researchers have found that brain activity occurs in discrete clumps or clusters, and the brain beats unevenly in all clusters. According to Hudson, anesthetized rodents always have a small amount of activity. This mode depends on the amount of anesthesia the subject receives, and the brain spontaneously jumps from one activity mode to another. Some activity patterns act as the "center" of the return path to consciousness, and the related activity patterns are consistent with those observed under deep anesthesia and light anesthesia.

　　This study proposes a new way to think about the human brain under anesthesia, and may encourage doctors to reconsider how to monitor anesthesia in the operating room. In addition, depending on how this result is applied to other diseases such as coma and minimal consciousness, doctors can better recover from brain damage by observing spontaneous jumps in brain activity. This is very predictable.