Scientists look for new technologies to improve the effectiveness of stem cell therapy

  Many years ago, the discovery of mesenchymal stem cells enabled scientists to make great progress in the field of regenerative medicine. Bone marrow mesenchymal stem cells can produce bone, fat and muscle tissues, and are currently mainly used for tissue repair. Clinical trials in China have shown that mesenchymal stem cells are not satisfactory. The problem is that stem cells cannot stay in the body and exert beneficial effects. In a recent research paper published in the international journal PNAS, researchers at the Harvard Stem Cell Institute showed that the transplantation of mesenchymal stem cells that can flow with angiogenic cells effectively enhances the clinical treatment effect. Through research, we found that we can improve. This co-transplantation effect promotes a longer survival period of mesenchymal stem cells in mice, provides mesenchymal stem cells with huge regeneration capabilities, and generates new bone and adipose tissue in recipient mice. I can. ..

  Researcher Dr. Melero-Martin said that when mesenchymal stem cells are transplanted into our body, the loss is very large, because the human body cannot provide me with the nutrients needed by mesenchymal stem cells. Say it quickly. The human mesenchymal stem cells are very close to the capillaries and can continuously receive signals from the capillaries. When researchers isolated mesenchymal stem cells from a laboratory dish, the communication between the stem cells and capillaries was interrupted, but the mesenchymal stem cells learned how to "feed" themselves. Therefore it has no effect. The researchers said that when

  When mesenchymal stem cells are reinjected into the body, the mesenchymal stem cells will not die close to the capillaries for a period of time, and die again; Melero-Martin is currently seeking differentiated stem cells to receive special signals from angiogenic cells without passing through The cell itself mimics this signal. There is no direct correlation between the many application values of mesenchymal stem cells. In this study, the researchers used mesenchymal stem cells as the basis for promoting tissue regeneration and demonstrated how they affect the use of mesenchymal stem cells in other fields. My personal opinion is different.