Scientists extend the preservation time of rat liver for transplantation

  Thanks to the efforts of scientists, the preservation and preservation period of rat liver used for organ transplantation has been significantly extended to 4 days. A study published in "Natural Medicine" found that it may directly solve the current crisis of insufficient human organ donation.

  Due to the limitations of current traditional organ storage methods, human organs can only be stored for 6-12 hours. Extending the retention period of human organs can have a significant impact on clinical cases of liver transplantation. Physicians will have more time to actively prepare recipients for organ transplantation, and at the same time provide more sources of donated organs from a geographical perspective. Korkut Uygun et al. used a method based on non-frozen (or ultra-cold) tissue preservation combined with in vitro machine perfusion, and reported that rats were transplanted after the liver was preserved for three days. It has been proved that its survival rate can reach 100%.

  The survival rate of liver transplantation rats stored for 4 days can reach 60% in the next month. In contrast, all rat livers preserved for 3 days using traditional methods are necrotic and cannot be used.