动物造模,干细胞 z-bo 2022-02-04 372

　　Researchers in the Ka laboratory have discovered a new method of using the regeneration ability of stem cells in the laboratory to regenerate dog teeth in the open laboratory of "Gene and Stem Cell Technology" of Kazan Federal University in Kazan. The method used is to separate stem cells from the dog’s omentum and subcutaneous fat, place the separated stem cells in porous pellets made of biocompatible titanium materials, and then place them in the defective teeth of the experimental dogs. Use gums. As a result of the experiment, stem cells began to grow and differentiate to form blood supply tissue, and shortly after, tooth tissue was formed in the tooth defect of the experimental dog.

　　The use of stem cell technology for tooth regeneration has a long history. Recently, scientists at Harvard University in the United States used low-intensity lasers to stimulate the bare tooth structure and underlying soft tissues of experimental mice, thereby activating a growth factor called TGF-β to stimulate stem cells. Stimulates dentin regeneration. Researchers at the Institute of Medical Research of the Japanese Research Institute of the University of Tokyo removed bacteria from the teeth of the dog, extracted stem cells from the teeth, cultured them with collagen fibers, and then implanted them into the dog’s jaw. After 20 weeks, the dog had teeth. Chinese researchers induced human pluripotent stem cells in urine, induced pluripotent stem cells into epithelial membrane-like structures, and mixed them with mouse tooth germ mesenchymal cells in mice. I gave "seeds" in the kidneys. About 3 weeks later, I "implanted" a batch of "regenerated teeth" of about 1 cubic millimeter.

　　Facts have proved that scientists from different countries have adopted different methods and made different attempts, but I think that in the near future, dental restoration will enter our lives.