【Animal Modeling】-Evaluation of the Validation Results for the Detection of Esterase-1 in the Serum of Experimental Mice

  Objective: Through the detection and comparison of esterase-1 in the serum of experimental mice, to promote the national laboratory animal quality testing laboratories to strengthen the quality control management and improve the detection ability.

  Method: Prepare proficiency testing samples according to standard procedures, number them randomly, and distribute them to participating units through cold chain transportation. Participants submit test results and copies of original records within a specified time limit. If the obtained result is completely consistent with the sample pre-inspection result, it is judged as a satisfactory result, otherwise it is an unsatisfactory result.

  Results: A total of 11 laboratories signed up to participate in this comparison test, of which 10 laboratories were satisfied with the results, accounting for 90.9% of the participating laboratories; 1 laboratory was dissatisfied with the results, accounting for 90.9% of the participating laboratories. 9.1%.

  Conclusion: This proficiency testing project reflects that the overall detection level of esterase-1 in experimental mouse kidney homogenate is relatively high in the participating laboratories, but it is still necessary to pay attention to standard specifications and detection details.