动物造模 z-bio 2022-06-16 499

　　Objective To study the alleviating effect of environmental enrichment on the stress response of experimental British Shorthair cats.

　　Methods 14 experimental British shorthair cats were randomly divided into welfare group and control group according to the presence or absence of environmental enrichment interventions, with 7 cats in each group. The experiment lasted for 11 weeks. The blood physiological and biochemical indicators, neuroendocrine indicators and immunological indicators of the experimental cats in each group were measured, analyzed and compared, and the stress levels of different groups were evaluated.

　　Results The average red blood cell volume of the welfare group was significantly smaller than that of the control group (P<0.05), the percentage of lymphocytes was significantly larger than that of the control group (P<0.01), and the percentage of neutrophils was significantly smaller than that of the control group (P<0.01). In addition, the levels of urea, creatinine, globulin and total protein in the welfare group were significantly lower than those in the control group (P<0.05), and the two indicators of epinephrine and dopamine were also significantly lower than those in the control group (P<0.05). interferon-γ, IFN-γ, interleukin (IL)-1β, IL-2, IL-4, IL-5, IFN-γ/IL-4 ratio, IL-2/IL-4 The ratio, IFN-γ/IL-5 ratio and IL-2/IL-5 ratio were higher than those in the control group; among which IFN-γ, IL-2, IFN-γ/IL-5 ratio and IL-2/IL-5 The ratio was significantly different (P<0.05), and the IL-5 difference was extremely significant (P<0.01).

　　Conclusion Taking the intervention measures with rich environment can effectively improve the welfare level of experimental cats and relieve the stress response.