基因突变 z-bo 2020-08-18 588

　　Researchers in the United Kingdom and the Netherlands have recently discovered that the "father" of chimpanzees is more likely to pass the mutated gene to offspring as they age. The results of the study come from animal studies, but the results indicate the influence of the father’s childbearing age on heredity. The University of Oxford welcomes researchers from the Foundation's Center for Human Genetics and the University of Oxford's Primate Biomedical Research Center to publish a paper in the new edition of "American Science" that found that chimpanzees are "parents." The genetic mutation in this part is inherited there, but the reproductive age of the chimpanzee "father" has a significant effect on this mutation. The average childbearing age of the chimpanzee "father" has tripled its genetic mutations. Oxford University

　　Professor Gil McWayne explained: "In the chimpanzee population, about 90% of the genetic mutations come from the "father", and about 75% in humans. "In humans, each person inherits about 70 genetic mutations from their parents on average. "However, this number is affected by the father’s age at birth. Older fathers pass on more genetic variation to their offspring. On average, an extra year of birth will result in two additional genetic mutations.

　　The participation of researchers believes that the risk of genetic variation is related to the father’s age at birth. Because male sperm keep dividing and reproducing, females shed all egg cells from birth. Earlier studies have confirmed that the father’s age at childbirth is at risk of developing certain diseases such as schizophrenia and autism. In addition, genetic variation is associated with the risk of certain other genetic diseases.