动物造模 z-bio 2022-10-21 504

　　Objective To investigate the inhibitory effect of a common commercially available Camellia oleifera powder on high-fat diet (HFD)-induced hyperlipidemia.

　　Methods 40 male SD rats were selected and randomly divided into 5 groups according to their body weight. The normal control group was given the control diet, and the other groups were given the high-fat diet. After 2 weeks, the gavage was stopped for 2 weeks. From the second week onwards, blood was collected from the submandibular vein every weekend to detect serum lipid levels.

　　Results At the end of 2 to 6 weeks, the total cholesterol level of the high-fat diet group was significantly higher than that of the normal control group (P<0.001, P<0.05, P<0.01, P<0.01, P<0.01, P<0.01, P<0. 05). From 2 to 4 weekends, the total cholesterol in the low-dose Camellia oleifera group was significantly lower than that in the simple high-fat diet group (P<0.05, P<0.05, P<0.01). At 3 to 4 weeks, the triglycerides in the high-dose Camellia oleifera group were significantly lower than those in the simple high-fat diet group (P<0.05, P<0.01).

　　Conclusion The Camellia oleifera powder can inhibit the increase of blood lipids caused by high-fat diet.