[Animal Modeling]-Experimental mice become "transparent" to help understand the 3D structure of organs

  By removing the color of the tissue, the researchers helped make the experimental mice transparent and visible, thereby exploring how cancer cells spread and finding a panacea for cancer. It kills the mouse gradually while the tissue color disappears, without dissecting and examining individual organs or entire organs. It also provides a clearer perspective for studying the spread of cancer cells. The University of Tokyo (University of Tokyo) and the Japan Science and Technology Agency (Japan Science and Technology Agency) injected physiological saline into the heart of rats to squeeze the blood in the circulatory system and squeeze hemoglobin in the rat to achieve transparency. Has been achieved. Soak the reagents for 2 weeks before being used in research.

  The author of "American Cell" magazine believes that this technology can give scientists a new understanding of the 3D structure of organs and the expression of genes in different tissues. You can use the microscope to see the details of the object, but it does not ultimately bring the overall view. Researcher Yuki Ueda said that this method can study the development of autoimmune diseases, such as embryos and cancer, from the cytological stage, and find new strategies to treat these diseases.