动物造模 z-bio 2023-03-23 399

　　OBJECTIVE: To investigate the method of preventing the displacement of the implanted dilator in the sarcoid and deep fascia of rabbits.

　　Methods: Forty common-grade experimental rabbits were randomly divided into two groups, namely the experimental group of 20 and the control group of 20. The deep surface of the skin and sarcoma on one side of the back was submerged and separated from the incision to form an implantation cavity. Around the cavity, the sarcoma and deep fascia were sutured intermittently with 3-0 silk threads, and a 50 mL kidney-shaped silicone rubber soft tissue expander was implanted. . One week after the operation, black thorns were made at four points around the dilator with a puncture machine to mark the position of the dilator. The experimental group started to inject water 2 months after the operation until the total amount reached 140 mL; the control group started to inject water 1 week after the operation until the total amount reached 140 mL. Complications such as whether the dilator was displaced during water injection, whether the incision was split, whether the injection pot was turned over, and the mortality of the animals were observed and recorded respectively.

　　RESULTS: There was no dilator displacement in the experimental group, and 4 rabbits in the control group had dilator displacement in the surviving animals. There was a statistically significant difference in the dilator displacement between the two groups (P<0.05﹚; experimental="" .="" although="" the="" incidence="" of="" incision="" dehiscence="" in="" dilation="" period="" rabbits="" was="" lower="" than="" that="" control="" there="" no="" statistical="" significance="" between="" two="" groups="" p="">0.05). Statistical significance (P>0.05﹚.

　　Conclusion: The surgical method of separation cavity internal fixation and delayed expansion can effectively prevent the displacement of the dilator between the sarcoma and deep fascia of rabbits, and achieve effective expansion.