动物实验,脑神经调节 z-bo 2020-08-20 558

　　Researchers at Northwestern University in the United States recently studied brain regions related to learning, memory, and stress response, and found that the brains of men and women have different modes of action at the molecular level. done

　　Many brain diseases occur in different genders, but how the underlying biological processes drive these differences is still a mystery. Neuroscientists at Northwestern University have discovered that men and women have essential differences in the molecular regulation of hypothalamic synapses.

　　Researchers can develop different treatments based on gender, rather than explaining why people are more likely to read maps, or why there are more men than women in certain occupations. I point out that learning is important. In this study, the researchers discovered that a drug called URB-597 modulates the release of key neurotransmitters, and it affects women rather than men.

　　It was found that the main brain endocannabinoid anandamide can enhance the inhibitory effect and reduce the release of neurotransmitters, but this effect does not exist in the brain of male rats. Endocannabinoid molecules are involved in many physiological processes, such as memory, appetite, pain and epilepsy, and are a very important class of molecules in the human body. Understanding the synthesis, release, and degradation processes of endocannabinoids has broad hints for understanding normal and pathological abnormal brain functions.

　　Researchers discovered that although this study was conducted using rats as an experimental model, many scientists who study elemental cannabinoids can still find these drugs and other similar drugs under clinical validation. He pointed out that he may not know the molecule yet. Since regulations vary by gender, there are also important hints in human research.