动物实验,当归补血汤 z-bo 2020-08-20 576

　　Objective: To observe the protective effect of Danggui Buxue Decoction on mice irradiated with 60C0-γ rays.

　　Method: The experimental mice were randomly divided into 5 groups (normal control group, model group, Danggui Buxue Decoction low, medium and high dose groups). Except for the normal control group, each group of mice was given a 60C0-γ radiation source. We have established a radiation injury model, which contains peripheral blood neutrophils (NEUT), bone marrow nucleated cells (BMC), serum superoxide dismutase (SOD) activity and serum C in each group of mice. Dialdehyde (MDA). Determine the amount.

　　Result: NEUT, BMC and SOD activities of radiation-damaged mice were significantly reduced (P \u003c0.01), and MDA content increased (P \u003c0.01). Danggui Buxue Decoction can increase NEUT, BMC and SOD activities in mice after radiation injury, and reduce MDA content. In addition, the high-dose Danggui Buxue Decoction group had a higher protective effect on radiation-damaged mice (P\u003c0.01).

　　Conclusion: Danggui Buxue Decoction has a certain protective effect and can prevent ionization damage in irradiated mice, which is related to the dose.