动物实验,子宫内膜异位 z-bo 2020-08-20 615

　　Objective: To establish a mouse model of endometriosis and observe the effect of endometriosis on the fertility of model mice.

　　Methods: The "peritoneum + subcutaneous" allogeneic endometrial injection method was used to establish a mouse model of endometriosis. The pregnancy rate and live birth rate were compared with the sham operation group and the blank group; the pregnancy ability of the ectopic disease on the model mice Impact.

　　Results: Two weeks after modeling, the mice had endometriotic lesions in the subcutaneous and abdominal cavity, which were divided into three groups: model group, sham operation group and blank group. By testing fertility, the pregnancy rates between the three groups were significantly different (P\u003c0.05).