动物造模 z-bio 2022-11-02 439

　　Objective: To investigate the detection method of somatosensory evoked potential (SEP) in beagle penis under general anesthesia and the changes of SEP during dorsal penile nerve resection, so as to provide reference for further research.

　　Methods: The somatosensory evoked potentials (SEPs) of the penis head and the dorsal penile nerve were detected in 5 beagle dogs during dorsal penile neurectomy under general anesthesia, and the waveform and parameter values were observed.

　　Results: Stable GPSEP and DNSEP waveforms were obtained in beagles under general anesthesia. The average latency of GPSEP was (41.84 ± 1.41) ms and the average amplitude was (1.56 ± 0.26) ms in 5 beagles under general anesthesia μ V; The average latency of DNSEP was (33.46 ± 2.45) ms, and the average amplitude was (1.80 ± 0.52) ms μ V。 The latency of DNSEP and GPSEP changed significantly during dorsal penile nerve resection in beagle dogs (P<0.05).

　　Conclusion: The detection of penis somatosensory evoked potential under general anesthesia is feasible and the waveform is stable; DNSEP and GPSEP latency may change during dorsal penile nerve resection, which is expected to provide experimental animal basis for further research.