干细胞疗法,动物实验 z-bo 2020-08-22 473

　　Stem cell therapy can regenerate human tissues damaged by trauma, disease or aging. According to the latest news from the University of South Wales (UNSW) in Australia, the university’s research team has made breakthroughs in this field and successfully conducted animal research. And this treatment will be realized within a few years. It will be realized. Related papers were recently published in the Proceedings of the National Academy of Sciences. The principle of this repair method is similar to the regeneration of the axillary process and can be used to repair different types of tissues. It is expected to change the current regenerative medicine treatment methods.

　　In a new study, researchers extracted bone and fat cells, stopped their memory, and turned them into induced pluripotent stem cells (iMS). They used 5-AZA (5-azacytidine) in combination with PDGF-AB (platelet-derived growth factor-AB) for about 2 days, and then treated with growth factor alone for 2-3 weeks to treat the damaged tissue. I have already inserted. They proliferate and promote tissue growth and healing. The lead author of the paper, Associate Professor John Pimanda of the University of New South Wales, said that this technology is a fundamental advance because iMS can regenerate many types of tissue. Washi Zandkanran, the first author of the paper, pointed out that many other stem cell therapies are still being studied and have many shortcomings. The use of viruses to induce stem cells is not clinically acceptable. On the contrary, new technology is progress. "We believe that new technologies will overcome these problems."

　　Eurosurgeon, Ralph Movers of the Prince of Wales Clinic College in New South Wales, said that the treatments are neck and back pain, disc injuries, joints and muscles. It is said that it has great potential in other fields and can also promote the recovery of bones and joints after surgery. By implanting reprogrammed stem cells, the intervertebral disc implant can better integrate with the patient's own bones.

　　Currently, the research team is evaluating whether adult fat cells can be reprogrammed into iMS. This can safely and effectively repair damaged tissues in mice.