The Greek word "Chimera" is named after a lion's head, a sheep's body and a basilisk monster in Greek mythology. Scientists claim that at least two sets of biological mosaics consist of cells of different genotype mosaics. In a recent study, researchers transplanted human stem cells into pig embryos to create this chimera. These "half-human, half-pig" embryos are no different from normal pig embryos, but the pancreas in the body is completely grown from human cells.
Many people worry that scientists will inadvertently create animals with human brain parts and even human consciousness and thinking capabilities. After animal sperm and egg-bearing animal embryos mate to produce animal human embryos, their mating is of further concern.
However, scientists believe that the scientific community can take measures to prevent such consequences. On the other hand, the results of this research provide a very valuable tool for medical research, allowing animals carrying human heart, kidney, liver and pancreas to undergo organ transplantation.
Due to moral controversy, the US federal government has restricted the conduct of such experiments. However, the National Institutes of Health (NIH) is now planning to issue a new "Chimera" trial reimbursement policy. They will keep the chimera in the pig for 28 days before removing the embryonic tissue from the pig's uterus for analysis. In addition, they even considered agreeing to use human sperm and eggs for more basic experiments to breed animals to study human development and infertility.
Carrie Wolinettes, deputy director of the IH Science and Policy Department (Carrie Wolinettes), wrote on her blog: “Finally, we not only want humans to understand this disease, but also want to ensure the progress of this research. This is also important for promoting human health. Very important.” I believe that these policy changes can promote the development of this frontier field in a responsible manner.