动物实验 z-bo 2020-08-26 589

　　In a recent research report published in the international journal TheFASEBJournal, researchers at the University of Tennessee Health Sciences Center discovered the chemical activation of β-LGND2 mediated by the estrogen receptor β in harmful fats in mice. (Fat) can be converted into beneficial fat (brown fat), which may reduce the risk of obesity and metabolic disorders. Brown fat may significantly increase metabolism and promote weight loss. Although people generally believe that obesity is not a life-threatening disease, researcher Ramesharayanan (Ramesharayanan) said that obesity is the cause of many fatal diseases and suggested that obesity is a safe and effective treatment for obesity in clinical practice. . urgent need. The targeting effect of ER-β seems to be a new strategy to safely fight against obesity. To conduct this study, the researcher Narayanan and colleagues used three groups of mice for the study. The first group of mice were fed a normal rodent diet, while the other two groups of mice were fed a high-fat diet to speed up the diet. One group of high-fat fed mice was treated with vehicle, and the other group of mice was treated with β-LGND2.

　　The researchers found that compared with other high-fat diet mice, β-LGND2 was used for treatment, and the mice were significantly thinner. The mice treated with β-LGND2 had higher body temperatures. They found that these mice were affected by higher oxygen consumption. Has a high metabolic rate. In many parts of the world, editor-in-chief Tall Pederson said the symptoms of pre-diabetic metabolic syndrome and obesity itself will continue to threaten the health of millions of people. Currently, more researchers are needed to participate in similar related research. With the latest research data, I have known for a long time that fat in the body can exist in two physiological forms, but this article will explore the beneficial pharmacological changes of fat. And I am more concerned about how to promote the conversion of harmful fats, which are beneficial to fats, thereby helping to reduce obesity.