Objective: To study the changes of hematopoietic system in mice after long-term intake of Polygonum multiflorum.
Method: The mice were randomly divided into 2 groups, the control group was fed with a normal diet, and the Polygonum multiflorum diet group fed with the multiflorum diet was sacrificed after 10 months. The peripheral blood and spleen were flow cytometry. Analyze various cells of thymus and bone marrow by measurement.
Result: In the wool flower root feeding group, the B cells of the spleen of the mice increased, the CD4 + cells of the thymus increased, and the CD8 + cells decreased. Bone marrow hematopoietic stem cells decreased significantly, during which quiescent cells increased, and proliferation and dividing cells decreased.
Conclusion: Long-term and correct intake of Polygonum multiflorum can help delay the aging of the hematopoietic system in mice and maintain the stability of the hematopoietic system.