【Animal modeling】-Comparison of drug-induced syndromes induced by prednisolone in different strains of mice

To study the differences in the degree of suppression of adrenal cortex function and the induction of drug-induced syndromes after glucocorticoids act on different strains of mice...

2022-11-29

【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...

2022-11-29

【Animal Modeling】-Acupuncture improves symptoms of insomnia rats and effects on spontaneous activity by regulating GABA-Gln metabolism

To study the improvement of symptoms of acupuncture on insomnia rats and its effect on spontaneous activity, and to explore its possible mechanism...

2022-11-29

【Animal modeling】-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

To study the dynamic changes and significance of oxidative stress and cytokines in the formation of nonalcoholic fatty liver disease (NAFLD) in gerbils...

2022-11-29

【Animal Modeling】-A Preliminary Study on the Localization of Microinjection in the Nucleus Solitarius of Rats

To explore the localization method of microinjection in the nucleus tractus solitarius of rats by applying different parameters of localization injection to improve the success rate and accuracy of injection...

2022-11-29

[Animal modeling] - Leptin regulates the signal transduction of liver fibrosis in rats and the intervention of mistletoe alkaloid

To investigate the signal transduction mechanism of leptin in regulating liver fibrosis in rats and the intervention effect of mistletine...

2022-11-28

【Animal modeling】-FGF-2/PELA/BMP-2 microcapsule scaffold promotes the osteogenic differentiation of rat periosteum-derived stem cells

To observe the effect of fibroblast growth factor-2/polylactic acid-polyethylene glycol-polylactic acid/bone morphogenetic protein-2 (FGF-2/PELA/BMP-2) microcapsule scaffold on the formation of periosteum-derived stem cells in SD rats. Bone different...

2022-11-28

【Animal Modeling】-Yuemai Jia Banxia Decoction reduces serum IgE and increases SOD activity in lung tissue of allergic asthma mice

To explore the effect of Yuemai Jia Banxia Decoction on allergic asthma mice by observing the changes in serum immunoglobulin (IgE) and superoxide dismutase (SOD) activity and inhibition rate in lung tissue of mice in different stages. mechanism of a...

2022-11-28

【Animal modeling】-Preparation and preliminary identification of rabbit anti-marmoset IgG-HRP-labeled antibody

To purify IgG antibody from marmoset serum, prepare rabbit anti-marmoset antiserum, and purify IgG from antiserum, HRP (horseradish peroxidase)-labeled rabbit anti-marmoset IgG...

2022-11-28

【Animal Modeling】-Establishment of an in vitro culture system of adult marmoset kidney cells and the application of CRISPR/Cas9 gene editing

To establish a culture system for in vitro culture of adult marmoset kidney cells, and to initially apply the Cas9 editing system to the cultured marmoset kidney cells to establish a system for detecting sgRNA cleavage activity...

2022-11-28

【Animal modeling】-Inhibitory effect of resveratrol on blood hypercoagulability in rats and its relationship with the expression of NF-κB

To study the effect of resveratrol on the formation of hypercoagulable state in rats and its relationship with the expression of NF-κB...

2022-11-28

【Animal Modeling】-A rapid method for extracting synovial membrane of rat knee joint

To establish a faster and more feasible method to obtain rat knee joint synovial tissue than traditional methods...

2022-11-28

【Animal modeling】-Effect of PM2.5 on reproductive endocrine level and pregnancy outcome in female mice

To study the effects of PM2.5 on reproductive endocrine hormone levels and pregnancy outcomes in female rats...

2022-11-28

【Animal Modeling】-A Modified Rat Jugular Vein Intubation for Autonomous Drug Administration and Its Application

To introduce an improved rat jugular vein cannula fabrication method and jugular vein cannulation operation method, and apply it to an experimental study of autonomous drug administration in rats to evaluate the service life and application effect of...

2022-11-28

【Animal modeling】-Observation of the anesthesia effect of compound anesthesia on Wuzhishan miniature pigs for up to 8 hours

To observe the general anesthesia effect of ketamine?Sumianxin II and midazolam mixture for induction of anesthesia, and ketamine and propofol to maintain anesthesia on Wuzhishan miniature pigs for up to 8 hours?...

2022-11-28

【Animal Modeling】-Albino C57BL/6N Mice Made by CRISPR-Cas9 Knockout of Tyr Gene

To obtain albino C57BL/6N mice and expand their application in skin transplantation and embryonic stem cell research...

2022-11-28