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Effect of Shouwu Prescription on Amino Acid Neurotransmitter Levels in the Brain of Rats with Levodopa-induced Dyskinesia

Effect of Shouwu Prescription on Amino Acid Neurotransmitter Levels in the Brain of Rats with Levodopa-induced Dyskinesia

To observe the effects of Shou wu fang (SWF), a traditional Chinese medicine, on the behavioral indicators of levodopa-induced dyskinesias (LID) model rats and the amino acid neurotransmitters in the brain, and to explore the intervention of Shouwu F...

2020-12-01
Establishment of rabbit brain death model by modified intracranial compression and its state maintenance

Establishment of rabbit brain death model by modified intracranial compression and its state maintenance

Explore improved intracranial compression method to make rabbit brain death model and methods to maintain brain death state...

2020-12-01
The role of RhoA/ROCK signaling pathway in a rat model of pulmonary hypertension caused by left heart disease

The role of RhoA/ROCK signaling pathway in a rat model of pulmonary hypertension caused by left heart disease

To explore the expression level and role of RhoA/ROCK signaling pathway in a rat model of pulmonary hypertension related to left heart disease...

2020-12-01
Establishment of an in vitro apoptosis model of rat nucleus pulposus cells

Establishment of an in vitro apoptosis model of rat nucleus pulposus cells

Establishment of an in vitro apoptosis model of rat nucleus pulposus cells...

2020-12-01
Establishment of Osteoporotic Tree Shrew Model by Ovariectomy

Establishment of Osteoporotic Tree Shrew Model by Ovariectomy

Reproduction of a postmenopausal osteoporotic tree shrew model with surgical bilateral ovarian castration...

2020-12-01
Comparison of in situ thoracic implantation and left ventricular injection to establish an animal model of lung cancer brain metastasis

Comparison of in situ thoracic implantation and left ventricular injection to establish an animal model of lung cancer brain metastasis

Provide a reliable modeling method for studying the mechanism of lung cancer brain metastasis...

2020-12-01
Ultrasound can remove plaque in a mouse model of Alzheimer\'s disease

Ultrasound can remove plaque in a mouse model of Alzheimer's disease

According to a new study, scanning ultrasound can help clear plaque and restore memory in a mouse model of Alzheimer\'s disease...

2020-11-30
Using mouse models of liver cancer to study human HCC is directly related

Using mouse models of liver cancer to study human HCC is directly related

Recently, researchers from Baylor College of Medicine in the United States published a new study in the international journal Nature Communication. They found that the co-activation of nuclear exogenous receptor CAR and β catenin can induce the proli...

2020-11-30
Current status and development of CRISPR/Cas9 technology and non-human primate disease models

Current status and development of CRISPR/Cas9 technology and non-human primate disease models

Gene editing methods for establishing animal models mainly include transgene and gene targeting...

2020-11-30
Scientists from the Chinese Academy of Sciences prepare a model of Parkinson\'s disease macaque for the first time

Scientists from the Chinese Academy of Sciences prepare a model of Parkinson's disease macaque for the first time

Parkinson’s disease is the world’s second largest neurodegenerative disease after Alzheimer’s, posing a serious threat to the health of middle-aged and elderly people...

2020-11-30
First preparation of ALS/dementia mouse model

First preparation of ALS/dementia mouse model

With the popular ice bucket challenge this summer, gradual freezing syndrome (ALS, amyotrophic lateral sclerosis) has attracted widespread public attention...

2020-11-30
The Chinese Academy of Sciences develops the first animal model of persistent hepatitis C virus infection

The Chinese Academy of Sciences develops the first animal model of persistent hepatitis C virus infection

The two human HCV receptors CD81 and OCLN were expressed in the liver of ICR mice using transgenic methods...

2020-11-30
Marmoset animal model susceptible to Middle East respiratory coronavirus

Marmoset animal model susceptible to Middle East respiratory coronavirus

Recently, in a research paper published in the international journal PLoS Pathogens, staff from the National Institute of Allergy and Infectious Diseases developed for the first time an animal model that can simulate the symptoms of Middle East Respi...

2020-11-30
Rodent models in drug development

Rodent models in drug development

In terms of cognitive ability research, researchers have made great progress using animal experiments. The next step is to build a rodent model that can be used for drug development...

2020-11-30
Autophagy activation can increase hippocampal neuron damage in rats with vascular dementia

Autophagy activation can increase hippocampal neuron damage in rats with vascular dementia

Immunohistochemical staining showed that the expression of autophagy-related protein Beclin-1 in hippocampal CA1 area decreased after wortmannin, an autophagy inhibitor, interfered with vascular dementia model rats...

2020-11-30
New breakthrough in personalized cancer treatment: constructing cancer mice that are the same as patients

New breakthrough in personalized cancer treatment: constructing cancer mice that are the same as patients

In a laboratory in Baltimore, USA, there is a scene where a hairless mouse is placed in rows of plastic boxes, and a yellow card is attached to each box. In fact, each mouse corresponds to a patient who is fighting cancer. These mice are the embodime...

2020-11-30