内页大图
Home > News > News
【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

To compare several key factors in the development of bacterial artificial chromosome transgenic mice, such as the genetic background of experimental mice, BAC plasmid injection concentration, BAC plasmid fragment size and BAC injection storage time,...

2022-04-20
【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

To study the role of calcineurin (CaN) and its downstream activated T cell nuclear factor (NFATc3) in restenosis after balloon dilation, and to provide a new theoretical basis for the prevention and treatment of vascular restenosis...

2022-04-20
【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

To compare the differences of glutamate-induced cell swelling by cultured astrocytes (AST) in Wistar rats and SD rats...

2022-04-20
【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat renal cells induced by high glucose...

2022-04-18
【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

To observe the effects of different doses of fluoride and aluminum combined with the duration of intake on longitudinal bone growth and bone metabolism in rats...

2022-04-18
【Animal Modeling】-Determination and Analysis of Hematology and Serum Biochemical Indexes in African Green Monkeys

【Animal Modeling】-Determination and Analysis of Hematology and Serum Biochemical Indexes in African Green Monkeys

To detect the hematology and serum biochemical indexes of 50 healthy African green monkeys, and to analyze the hematology and serum biochemistry of African green monkeys of different genders and age groups (young group: 1-3 years old, adult group: 4-...

2022-04-18
【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

To observe the effect of Xingnaojing injection on the dose-response relationship of Beagle dog coma...

2022-04-18
【Animal Modeling】-Xiamen University Efficiently Editing Plasmodium Genomes Using CRISPR/Cas9 System

【Animal Modeling】-Xiamen University Efficiently Editing Plasmodium Genomes Using CRISPR/Cas9 System

Using the CRISPR/Cas9 system, the research group of Professor Yuan Jing from the School of Life Sciences of Xiamen University has efficiently achieved different types of modifications of multiple genes in the Plasmodium genome, including gene deletio...

2022-04-18
【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

To investigate the role of long non-coding RNA (LncRNA) taurine up-regulated gene 1 (TUG1) regulating microRNA (miR)-137 involved in nerve injury in rats with focal cerebral ischemia...

2022-04-18
【Animal Modeling】-Optimization of the freezing method of cynomolgus monkey semen without yolk freezing solution

【Animal Modeling】-Optimization of the freezing method of cynomolgus monkey semen without yolk freezing solution

Due to the existence of uncertain components such as yolk in traditional sperm freezing solutions, there is a risk of biological contamination. Therefore, this study aimed to use Origio and Quinn\'s two commercial yolk-free cryopreservations to prese...

2022-04-18
【Animal Modeling】-Tail-clamped somatosensory stimulation inhibits the excitability of pyramidal neurons in the hippocampal CA1 region of rats

【Animal Modeling】-Tail-clamped somatosensory stimulation inhibits the excitability of pyramidal neurons in the hippocampal CA1 region of rats

Dr. Feng Zhouyan\'s team from Zhejiang University, China used microelectrode arrays to monitor neuronal activity in the hippocampus of rats, and found that the sensory stimulation of tail clipping would induce different types of neurons to produce di...

2022-04-18
【Animal Modeling】-Umbilical cord blood mononuclear cells promote angiogenesis in rats with acute myocardial infarction and its mechanism

【Animal Modeling】-Umbilical cord blood mononuclear cells promote angiogenesis in rats with acute myocardial infarction and its mechanism

To investigate the effect and mechanism of cord blood mononuclear cells (HCMNCs) on angiogenesis in acute myocardial infarction (AMI) rats...

2022-04-16
【Animal Modeling】-Effects of hesperidin on antioxidant activity and gene expression of antioxidant enzymes in mice

【Animal Modeling】-Effects of hesperidin on antioxidant activity and gene expression of antioxidant enzymes in mice

To investigate the effect of hesperidin (HDN) on the antioxidant effect of the body...

2022-04-16
【Animal Modeling】-Effect of Simvastatin Combined with Risedronate on Bone Loss Induced by Tail Suspension in Mice

【Animal Modeling】-Effect of Simvastatin Combined with Risedronate on Bone Loss Induced by Tail Suspension in Mice

To investigate and compare the effects of simvastatin and risedronate sodium alone or in combination on dexamethasone-induced osteoporosis in mice...

2022-04-16
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2022-04-16
【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

To investigate a method for reducing mortality in a lithium chloride-pilocarpine-induced status convulsive model by gastric gavage with modified oral rehydration salts...

2022-04-16