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【Animal Modeling】-Efficacy and safety of electroacupuncture combined with methylprednisolone on intervertebral disc prolapse in rats

【Animal Modeling】-Efficacy and safety of electroacupuncture combined with methylprednisolone on intervertebral disc prolapse in rats

To observe the effects of electroacupuncture combined with methylprednisolone and electroacupuncture or methylprednisolone alone on limb motor function and nerve cell Nissl bodies in rat models 24 hours after intervertebral disc prolapse, to provide...

2022-04-25
[Animal model]-Genetically modified rheumatoid arthritis (RA)

[Animal model]-Genetically modified rheumatoid arthritis (RA)

Human tumor necrosis factor transgenic mouse model [Modeling mechanism] Tumor necrosis factor-α (TNF-α) is mainly secreted by activated macrophages, activated T cells, NK cells and mast cells. It also secretes a small amount...

2022-04-25
【Animal Modeling】- Breeding and Genotyping of Type I Interferon Receptor (Ifnar) Knockout Mice

【Animal Modeling】- Breeding and Genotyping of Type I Interferon Receptor (Ifnar) Knockout Mice

To analyze the breeding and identification of Ifnar knockout mice, and to provide an ideal animal model for the study of various viruses...

2022-04-25
【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

To study the effect of vortioxetine, a novel antidepressant, on cyclic adenosine monophosphate/cyclic adenosine monophosphate response element binding protein/brain-derived neurotrophic factor (cAMP/CREB/BDNF) signal transduction pathway...

2022-04-25
【Animal Modeling】-Experimental Study on In Vitro Fertilization of Type Ⅰ Interferon Receptor Deficient Mice

【Animal Modeling】-Experimental Study on In Vitro Fertilization of Type Ⅰ Interferon Receptor Deficient Mice

To explore the effect of deletion of two type I interferon receptors on in vitro fertilization in mice and to optimize the conditions of in vitro fertilization...

2022-04-25
【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

The delayed response test based on the Wisconsin Universal Tester is a common method to evaluate the learning and memory ability of non-human primates. The experiment is affected by many factors during the process. The learning and memory ability has...

2022-04-24
【Animal Modeling】-Effect of repeated cold-heat stimulation on the immune barrier function of nasal mucosa in rats and the effect of TCM formula

【Animal Modeling】-Effect of repeated cold-heat stimulation on the immune barrier function of nasal mucosa in rats and the effect of TCM formula

To investigate the effect of repeated cold-heat stimulation on the immune barrier function of nasal mucosa in rats, and to investigate the effects of Mahuang Decoction and Yinqiao Powder, which are commonly used in traditional Chinese medicine...

2022-04-24
【Animal modeling】-Isolation of pancreatic islets from NOD mice and their biological characteristics in vitro and in vivo

【Animal modeling】-Isolation of pancreatic islets from NOD mice and their biological characteristics in vitro and in vivo

To establish a method for isolating and purifying pancreatic islets from non-obese diabetic (NOD) mice, and to study their biological properties in vitro and in vivo...

2022-04-24
【Animal Modeling】-Necrotic cells reverse the imbalance of Treg/Th17 ratio in septic mice

【Animal Modeling】-Necrotic cells reverse the imbalance of Treg/Th17 ratio in septic mice

To study the effect of pre-infusion of necrotic cells on the balance of Treg/Th17 cells in a mouse model of sepsis...

2022-04-24
【Animal modeling】-Construction and expression of human IL-37b gene eukaryotic expression vector

【Animal modeling】-Construction and expression of human IL-37b gene eukaryotic expression vector

To construct pEGFP-N1/IL-37b eukaryotic expression vector, and to detect its expression in THP-1 cells...

2022-04-24
【Animal Modeling】- Improvement of Rat Cerebrospinal Fluid Extraction by Negative Pressure Suction Device

【Animal Modeling】- Improvement of Rat Cerebrospinal Fluid Extraction by Negative Pressure Suction Device

To improve the extraction of cerebrospinal fluid from rats by negative pressure suction device, and to further improve the success rate of cerebrospinal fluid collection in rats...

2022-04-24
【Animal Modeling】-Results and Analysis of Laboratory Testing Ability for Salmonella in Laboratory Animals

【Animal Modeling】-Results and Analysis of Laboratory Testing Ability for Salmonella in Laboratory Animals

Through the proficiency testing plan for Salmonella detection in laboratory animals, to understand the detection ability of laboratory animal testing institutions for Salmonella, and to improve the quality detection level of laboratory animals...

2022-04-24
【Animal modeling】-Intervention effect and mechanism of down-regulation of miR-192 on renal interstitial fibrosis in rats with unilateral ureteral obstruction

【Animal modeling】-Intervention effect and mechanism of down-regulation of miR-192 on renal interstitial fibrosis in rats with unilateral ureteral obstruction

To investigate the intervention effect and mechanism of down-regulation of miR-192 on renal interstitial fibrosis in rats with unilateral ureteral obstruction (UUO) after renal injury...

2022-04-24
【Animal Modeling】-Effect of Tongxinluo Capsule on inflammatory response, brain edema and cognitive function in rats exposed to hypobaric hypoxia

【Animal Modeling】-Effect of Tongxinluo Capsule on inflammatory response, brain edema and cognitive function in rats exposed to hypobaric hypoxia

To investigate the neuroprotective effect of Tongxinluo capsule on cognitive impairment in rats exposed to acute hypobaric hypoxia and its related mechanism...

2022-04-24
【Animal Modeling】-Making Transplanted Lymphoma

【Animal Modeling】-Making Transplanted Lymphoma

Using established lymphoma cell lines or patient lymphoma tissue transplanted into immunodeficient animals, transplanted lymphoma models can be established and tumor characteristics can be characterized...

2022-04-24
【Animal Model】-Virus-induced brain tumor model

【Animal Model】-Virus-induced brain tumor model

Although Basquez Lopez (Basquez Lopez) was originally found to be able to induce tumors through a virus, its cause is not yet fully understood...

2022-04-24